A Resource Guide to GMP Compliance for a Safer, More Reliable Supply Chain


Good Manufacturing Practice (GMP) compliance is the blueprint for achieving a strong and secure and efficient supply chain. Without it, everything—safety, quality, and trust—risks collapsing, leaving your business vulnerable to disruptions and costly expenses. For 3PL providers like ProPack, GMP compliance is more than just a regulatory requirement with boxes to check – it’s a promise of excellence across all channels of your product’s distribution. 

What Is GMP Compliance?

At its core, GMP compliance is about consistency and control. It’s a set of strict regulations designed to ensure products are manufactured and handled according to established quality standards and is what keeps the supply chain running smoothly, safeguarding businesses and consumers by reducing  risks like contamination or recalls at every stage of the process.

The ten most impactful Good Manufacturing Practices and guidelines for your distribution include:

  • Quality Management
  • Standard Operating Procedures (SOPs)
  • Hygiene &Cleanliness
  • Design and Maintenance of Your Facility
  • Equipment Validation and Maintenance
  • Inspection of Raw Materials
  • Monitoring & Control of Production
  • Batch/Product Traceability
  • Product Testing
  • Regular Audits and Inspections

Why GMP Compliance Within Your Facility Is the Backbone of Supply Chain Safety

GMP compliance  acts as both a safety net and a guiding compass for your supply chain:

  • Risk Mitigation –GMP compliance ensures strict quality control measures are in place to prevent product defects, contamination, or recalls.
  • Regulatory Adherence –  Compliance with GMP keeps businesses on solid ground, ensuring they meet regulatory requirements and avoid penalties while staying ahead of evolving industry guidelines.

GMP v cGMP – What is the difference?

  • GMP (Good Manufacturing Practice) –  A set of basic guidelines ensuring products are consistently produced and controlled according to quality standards.
    • Example:  Written procedures, rigorous testing, regular audits, facility hygiene standards, and equipment maintenance for accurate batch production and traceability.
  • cGMP (Current Good Manufacturing Practice) –  cGMP regulations are an updated version of GMP that emphasizes staying current with modern technologies and practices.
    • Example: Automated monitoring systems for temperature control or blockchain for product traceability

What are the Benefits of Partnering with a GMP-Compliant 3PL Provider?

Partnering with a GMP-compliant 3PL provider like ProPack ensures your supply chain is built on a foundation of reliability. From strict quality controls that prevent contamination to detailed audits that catch potential issues before they arise, ProPack’s processes ensure product integrity at every stage, empowering you with tools that keep you informed about your inventory’s journey in real time.

How can I verify that my 3PL provider is GMP certified? 

We recommend asking for GMP certification records in addition to checking their compliance history through the FDA’s inspection database. 

How to become GMP Certified

To get GMP-certified, a business must set up a quality management system, properly train their team to meet outlined standards, and pass an audit focused onGMP facility requirements  from an accredited certification body. For more information, refer to the FDA’s GMP Guidelines.

A GMP compliant facility is a cornerstone of supply chain safety, protecting both businesses and consumers. ProPack’s dedication to GMP standards helps clients maintain regulatory compliance while ensuring high-quality supply chain operation across North America and Canada, always. Partner with ProPack to safeguard your supply chain with confidence.